Depletion of macrophages with clodronate liposomes partially attenuates renal fibrosis on AKI–CKD transition

AbstractClodronate liposomes are bisphosphonates encapsulated by liposomes that are known to induce macrophage depletion in vivo. In a previous study, clodronate liposomes improved renal ischemia/reperfusion (I/R) injury in mice, which may be due to effects on macrophage phenotypes. However, how inf...

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Bibliographic Details
Main Authors: Zhizhi Hu, Juan Zhan, Guangchang Pei, Rui Zeng
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Renal Failure
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2022.2149412