The impact of biological sex on the response to noise and otoprotective therapies against acoustic injury in mice

The impact of biological sex on the response to noise and otoprotective therapies against acoustic injury in mice

Abstract Background Noise-induced hearing loss (NIHL) is the most prevalent form of acquired hearing loss and affects about 40 million US adults. Among the suggested therapeutics tested in rodents, suberoylanilide hydroxamic acid (SAHA) has been shown to be otoprotective from NIHL; however, these re...

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Bibliographic Details
Main Authors: Béatrice Milon, Sunayana Mitra, Yang Song, Zachary Margulies, Ryan Casserly, Virginia Drake, Jessica A. Mong, Didier A. Depireux, Ronna Hertzano
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Biology of Sex Differences
Subjects:
Noise-induced hearing loss
Sex differences
SAHA
B6CBAF1/J mice
Inner ear
ABR
Online Access:http://link.springer.com/article/10.1186/s13293-018-0171-0

Internet

http://link.springer.com/article/10.1186/s13293-018-0171-0

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