Correlation between Sialylation Status and Cell Susceptibility to Amyloid Toxicity

Correlation between Sialylation Status and Cell Susceptibility to Amyloid Toxicity

The interaction between the cell membrane and misfolded protein species plays a crucial role in the development of neurodegeneration. This study was designed to clarify the relationship between plasma membrane composition in terms of the differently linked sialic acid (Sia) content and cell suscepti...

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Bibliographic Details
Main Authors: Eleonora Sgambati, Alessia Tani, Manuela Leri, Giovanni Delfino, Sandra Zecchi-Orlandini, Monica Bucciantini, Daniele Nosi
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cells
Subjects:
sialylation status
Aβ-42 toxicity
amyloid–plasma membrane interaction
cell differentiation
GM1
Online Access:https://www.mdpi.com/2073-4409/11/4/601

Internet

https://www.mdpi.com/2073-4409/11/4/601

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