Perivascular spaces as a marker of disease severity and neurodegeneration in patients with behavioral variant frontotemporal dementia

Perivascular spaces as a marker of disease severity and neurodegeneration in patients with behavioral variant frontotemporal dementia

BackgroundBehavioural Variant Frontotemporal Dementia (bvFTD) is a rapidly progressing neurodegenerative proteinopathy. Perivascular spaces (PVS) form a part of the brain’s glymphatic clearance system. When enlarged due to poor glymphatic clearance of toxic proteins, PVS become larger and more consp...

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Bibliographic Details
Main Authors: Jasmine Moses, Benjamin Sinclair, Daniel L. Schwartz, Lisa C. Silbert, Terence J. O’Brien, Meng Law, Lucy Vivash
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Neuroscience
Subjects:
Behavioural Variant Frontotemporal Dementia
frontotemporal lobar degeneration
perivascular spaces
tau
clinical trial
anti-tau therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.1003522/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2022.1003522/full

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