Propionibacterium acnes biofilm is present in intervertebral discs of patients undergoing microdiscectomy.

Propionibacterium acnes biofilm is present in intervertebral discs of patients undergoing microdiscectomy.

BACKGROUND:In previous studies, Propionibacterium acnes was cultured from intervertebral disc tissue of ~25% of patients undergoing microdiscectomy, suggesting a possible link between chronic bacterial infection and disc degeneration. However, given the prominence of P. acnes as a skin commensal, su...

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Main Authors: Manu N Capoor, Filip Ruzicka, Jonathan E Schmitz, Garth A James, Tana Machackova, Radim Jancalek, Martin Smrcka, Radim Lipina, Fahad S Ahmed, Todd F Alamin, Neel Anand, John C Baird, Nitin Bhatia, Sibel Demir-Deviren, Robert K Eastlack, Steve Fisher, Steven R Garfin, Jaspaul S Gogia, Ziya L Gokaslan, Calvin C Kuo, Yu-Po Lee, Konstantinos Mavrommatis, Elleni Michu, Hana Noskova, Assaf Raz, Jiri Sana, A Nick Shamie, Philip S Stewart, Jerry L Stonemetz, Jeffrey C Wang, Timothy F Witham, Michael F Coscia, Christof Birkenmaier, Vincent A Fischetti, Ondrej Slaby
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5378350?pdf=render

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http://europepmc.org/articles/PMC5378350?pdf=render

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