Deubiquitinating Enzyme USP7 Is Required for Self-Renewal and Multipotency of Human Bone Marrow-Derived Mesenchymal Stromal Cells

Deubiquitinating Enzyme USP7 Is Required for Self-Renewal and Multipotency of Human Bone Marrow-Derived Mesenchymal Stromal Cells

Ubiquitin-specific protease 7 (USP7) is highly expressed in a variety of malignant tumors. However, the role of USP7 in regulating self-renewal and differentiation of human bone marrow derived mesenchymal stromal cells (hBMSCs) remains unknown. Herein, we report that USP7 regulates self-renewal of h...

Full description

Bibliographic Details
Main Authors: You Ji Kim, Kwang Hwan Park, Kyoung-Mi Lee, Yong-Min Chun, Jin Woo Lee
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
USP7
deubiquitination
self-renewal capacity
multipotential capacity
SOX2
hBMSCs
Online Access:https://www.mdpi.com/1422-0067/23/15/8674

Internet

https://www.mdpi.com/1422-0067/23/15/8674

Similar Items