Inhibition of NLRP3 attenuates sodium dextran sulfate-induced inflammatory bowel disease through gut microbiota regulation

Inhibition of NLRP3 attenuates sodium dextran sulfate-induced inflammatory bowel disease through gut microbiota regulation

Background: Inflammatory bowel disease (IBD) is a chronic, life-threatening inflammatory disease of gastrointestinal tissue characterized by inflammation of the gut. Recent studies have shown that gut microbiota is involved in the pathophysiology of IBD. However, it is unknown whether direct inhibit...

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Bibliographic Details
Main Authors: Shi-Le Wang, Man-Man Zhang, Han Zhou, Guo-Qiang Su, Yi Ding, Guang-Hui Xu, Xu Wang, Cheng-Fu Li, Wei-Feng Huang, Li-Tao Yi
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Biomedical Journal
Subjects:
NLRP3
Inflammatory bowel disease
Microbiota
Cytokine
Dextran sulfate sodium
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417023000045

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http://www.sciencedirect.com/science/article/pii/S2319417023000045

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