Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors

Discovery and Development Strategies for SARS-CoV-2 NSP3 Macrodomain Inhibitors

The worldwide public health and socioeconomic consequences caused by the COVID-19 pandemic highlight the importance of increasing preparedness for viral disease outbreaks by providing rapid disease prevention and treatment strategies. The NSP3 macrodomain of coronaviruses including SARS-CoV-2 is amo...

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Bibliographic Details
Main Authors: Marion Schuller, Tryfon Zarganes-Tzitzikas, James Bennett, Stephane De Cesco, Daren Fearon, Frank von Delft, Oleg Fedorov, Paul E. Brennan, Ivan Ahel
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pathogens
Subjects:
ADP-ribosylation
macrodomain
SARS-CoV-2
COVID-19
non-structural protein 3 (NSP3)
drug discovery and development
Online Access:https://www.mdpi.com/2076-0817/12/2/324

Internet

https://www.mdpi.com/2076-0817/12/2/324

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