Wnt signal-dependent antero-posterior specification of early-stage CNS primordia modeled in EpiSC-derived neural stem cells

Wnt signal-dependent antero-posterior specification of early-stage CNS primordia modeled in EpiSC-derived neural stem cells

The specification of the embryonic central nervous system (CNS) into future brain (forebrain, midbrain, or hindbrain) and spinal cord (SC) regions is a critical step of CNS development. A previous chicken embryo study indicated that anterior epiblast cells marked by Sox2 N2 enhancer activity are spe...

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Bibliographic Details
Main Authors: Kae Nakamura, Yusaku Watanabe, Claire Boitet, Sayaka Satake, Hideaki Iida, Koya Yoshihi, Yasuo Ishii, Kagayaki Kato, Hisato Kondoh
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
epiblst
CNS primordia
anteroposterior regionalization
CNS subdivisions
Wnt signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1260528/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1260528/full

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