A practical two-step procedure for the preparation of enantiopure pyridines: Multicomponent reactions of alkoxyallenes, nitriles and carboxylic acids followed by a cyclocondensation reaction

A practical approach to highly functionalized 4-hydroxypyridine derivatives with stereogenic side chains in the 2- and 6-positions is described. The presented two-step process utilizes a multicomponent reaction of alkoxyallenes, nitriles and carboxylic acids to provide β-methoxy-β-ketoenamides which...

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Váldodahkkit: Christian Eidamshaus, Roopender Kumar, Mrinal K. Bera, Hans-Ulrich Reissig
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Beilstein-Institut 2011-07-01
Ráidu:Beilstein Journal of Organic Chemistry
Fáttát:
Liŋkkat:https://doi.org/10.3762/bjoc.7.108