A comparative approach linking molecular dynamics of altered peptide ligands and MHC with in vivo immune responses.

<h4>Background</h4>The recognition of peptide in the context of MHC by T lymphocytes is a critical step in the initiation of an adaptive immune response. However, the molecular nature of the interaction between peptide and MHC and how it influences T cell responsiveness is not fully unde...

Full description

Bibliographic Details
Main Authors: Bernhard Knapp, Ulrich Omasits, Wolfgang Schreiner, Michelle M Epstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20657836/?tool=EBI