Humans Surviving Cholera Develop Antibodies against <named-content content-type="genus-species">Vibrio cholerae</named-content> O-Specific Polysaccharide That Inhibit Pathogen Motility

ABSTRACT The mechanism of protection against cholera afforded by previous illness or vaccination is currently unknown. We have recently shown that antibodies targeting O-specific polysaccharide (OSP) of Vibrio cholerae correlate highly with protection against cholera. V. cholerae is highly motile an...

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Main Authors: Richelle C. Charles, Meagan Kelly, Jenny M. Tam, Aklima Akter, Motaher Hossain, Kamrul Islam, Rajib Biswas, Mohammad Kamruzzaman, Fahima Chowdhury, Ashraful I. Khan, Daniel T. Leung, Ana Weil, Regina C. LaRocque, Taufiqur Rahman Bhuiyan, Atiqur Rahman, Leslie M. Mayo-Smith, Rachel L. Becker, Jatin M. Vyas, Christina S. Faherty, Kourtney P. Nickerson, Samantha Giffen, Alaina S. Ritter, Matthew K. Waldor, Peng Xu, Pavol Kováč, Stephen B. Calderwood, Robert C. Kauffman, Jens Wrammert, Firdausi Qadri, Jason B. Harris, Edward T. Ryan
Format: Article
Language:English
Published: American Society for Microbiology 2020-12-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.02847-20