Diminished androgen levels are linked to irritable bowel syndrome and cause bowel dysfunction in mice

Diminished androgen levels are linked to irritable bowel syndrome and cause bowel dysfunction in mice

Functional gastrointestinal disorders (FGIDs) have prominent sex differences in incidence, symptoms, and treatment response that are not well understood. Androgens are steroid hormones present at much higher levels in males than females and could be involved in these differences. In adults with irri...

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Bibliographic Details
Main Authors: Daniella Rastelli, Ariel Robinson, Valentina N. Lagomarsino, Lynley T. Matthews, Rafla Hassan, Kristina Perez, William Dan, Peter D. Yim, Madison Mixer, Aleksandra Prochera, Amy Shepherd, Liang Sun, Kathryn Hall, Sarah Ballou, Anthony Lembo, Judy Nee, Meenakshi Rao
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-01-01
Series:The Journal of Clinical Investigation
Subjects:
Gastroenterology
Neuroscience
Online Access:https://doi.org/10.1172/JCI150789

Internet

https://doi.org/10.1172/JCI150789

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