Modelling of the dynamic polarizability of macromolecules for single-molecule optical biosensing

Abstract The structural dynamics of macromolecules is important for most microbiological processes, from protein folding to the origins of neurodegenerative disorders. Noninvasive measurements of these dynamics are highly challenging. Recently, optical sensors have been shown to allow noninvasive ti...

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Bibliographic Details
Main Authors: Larnii S. Booth, Eloise V. Browne, Nicolas P. Mauranyapin, Lars S. Madsen, Shelley Barfoot, Alan Mark, Warwick P. Bowen
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05586-0