Modelling of the dynamic polarizability of macromolecules for single-molecule optical biosensing
Abstract The structural dynamics of macromolecules is important for most microbiological processes, from protein folding to the origins of neurodegenerative disorders. Noninvasive measurements of these dynamics are highly challenging. Recently, optical sensors have been shown to allow noninvasive ti...
Main Authors: | Larnii S. Booth, Eloise V. Browne, Nicolas P. Mauranyapin, Lars S. Madsen, Shelley Barfoot, Alan Mark, Warwick P. Bowen |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-05586-0 |
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