Anti-inflammatory reprogramming of microglia cells by metabolic modulators to counteract neurodegeneration; a new role for Ranolazine

Anti-inflammatory reprogramming of microglia cells by metabolic modulators to counteract neurodegeneration; a new role for Ranolazine

Abstract Microglia chronic activation is a hallmark of several neurodegenerative diseases, including the retinal ones, possibly contributing to their etiopathogenesis. However, some microglia sub-populations have anti-inflammatory and neuroprotective functions, thus making arduous deciphering the ro...

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Bibliographic Details
Main Authors: Ilaria Piano, Arianna Votta, Patrizia Colucci, Francesca Corsi, Sara Vitolo, Chiara Cerri, Dario Puppi, Michele Lai, José Fernando Maya-Vetencourt, Massimiliano Leigheb, Chiara Gabellini, Elisabetta Ferraro
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47540-8

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https://doi.org/10.1038/s41598-023-47540-8

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