A randomised preclinical trial of adrenaline use during cardiac arrest in mice

Background: Adrenaline is routinely administered during cardiac arrest resuscitation. Using a novel murine model of cardiac arrest, this study evaluates the effects of adrenaline use on survival and end-organ injury. Methods: A total of 58 mice, including cardiac arrest (CA) and sham (SHAM) groups r...

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Bibliographic Details
Main Authors: Daniel G. Donner, Jason E. Bloom, Waled A. Shihata, Aascha A. Brown, Rosalind Cook, Tsin Yee Tai, Gavin W. Lambert, Po-Yin Chu, William Chan, Dion Stub, Bing H. Wang, David M. Kaye
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Resuscitation Plus
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666520422000923