Adrenomedullin Enhances Mouse Gustatory Nerve Responses to Sugars via T1R-Independent Sweet Taste Pathway

Adrenomedullin Enhances Mouse Gustatory Nerve Responses to Sugars via T1R-Independent Sweet Taste Pathway

On the tongue, the T1R-independent pathway (comprising glucose transporters, including sodium–glucose cotransporter (SGLT1) and the K<sub>ATP</sub> channel) detects only sugars, whereas the T1R-dependent (T1R2/T1R3) pathway can broadly sense various sweeteners. Cephalic-phase insulin rel...

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Bibliographic Details
Main Authors: Shusuke Iwata, Ryusuke Yoshida, Shingo Takai, Keisuke Sanematsu, Noriatsu Shigemura, Yuzo Ninomiya
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Nutrients
Subjects:
taste
sweet taste
taste receptor family 1 members 2 and 3
sodium–glucose cotransporter 1
adrenomedullin
caloric sensing
Online Access:https://www.mdpi.com/2072-6643/15/13/2941

Internet

https://www.mdpi.com/2072-6643/15/13/2941

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