Genomic Island-Encoded Histidine Kinase and Response Regulator Coordinate Mannose Utilization with Virulence in Enterohemorrhagic Escherichia coli

Genomic Island-Encoded Histidine Kinase and Response Regulator Coordinate Mannose Utilization with Virulence in Enterohemorrhagic Escherichia coli

ABSTRACT Enterohemorrhagic Escherichia coli (EHEC) is a highly adaptive pathogen and has acquired diverse genetic elements, such as genomic islands and prophages, via horizontal gene transfer to promote fitness in vivo. Two-component signaling systems (TCSs) allow bacteria to sense, respond to, and...

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Bibliographic Details
Main Authors: Dawei Yang, Yongwu Yang, Pengfei Qiao, Fengwei Jiang, Xinyang Zhang, Zihui Zhao, Tao Cai, Ganwu Li, Wentong Cai
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mBio
Subjects:
enterohemorrhagic Escherichia coli
mannose metabolism
pathogenesis
type III secretion system
virulence regulation
Online Access:https://journals.asm.org/doi/10.1128/mbio.03152-22

Internet

https://journals.asm.org/doi/10.1128/mbio.03152-22

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