Light‐Dark Patterns Mirroring Shift Work Accelerate Atherosclerosis and Promote Vulnerable Lesion Phenotypes

Light‐Dark Patterns Mirroring Shift Work Accelerate Atherosclerosis and Promote Vulnerable Lesion Phenotypes

Background Despite compelling epidemiological evidence that circadian disruption inherent to long‐term shift work enhances atherosclerosis progression and vascular events, the underlying mechanisms remain poorly understood. A challenge to the use of mouse models for mechanistic and interventional st...

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Bibliographic Details
Main Authors: Mariana G. Figueiro, Young‐Hwa Goo, Ryan Hogan, Barbara Plitnick, Jeong‐Kyung Lee, Kiran Jahangir, Mousumi Moulik, Vijay K. Yechoor, Antoni Paul
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
atherosclerosis
circadian disruption
mice
shift work
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.018151

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.018151

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