A Review of Approaches to Potentiate the Activity of Temozolomide against Glioblastoma to Overcome Resistance

A Review of Approaches to Potentiate the Activity of Temozolomide against Glioblastoma to Overcome Resistance

A glioblastoma (GBM) is one of the most aggressive, infiltrative, and treatment-resistant malignancies of the central nervous system (CNS). The current standard of care for GBMs include maximally safe tumor resection, followed by concurrent adjuvant radiation treatment and chemotherapy with the DNA...

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Bibliographic Details
Main Authors: Aniruddha S. Karve, Janki M. Desai, Sidharth N. Gadgil, Nimita Dave, Trisha M. Wise-Draper, Gary A. Gudelsky, Timothy N. Phoenix, Biplab DasGupta, Lalanthica Yogendran, Soma Sengupta, David R. Plas, Pankaj B. Desai
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma
treatment resistance
combination therapeutics
Online Access:https://www.mdpi.com/1422-0067/25/6/3217

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https://www.mdpi.com/1422-0067/25/6/3217

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