Computational Design of New Teixobactin Analogues as Inhibitors of Lipid II Flippase MurJ

The peptidoglycan (PG) cell wall is an essential component of the bacterial cell structure, and crippling its synthesis is one of the most successful strategies in the continuing war against pathogenic bacteria. MurJ is a member of the multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) flippase s...

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Bibliographic Details
Main Authors: Andreea Calianu, Radu Tamaian
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Medical Sciences Forum
Subjects:
Online Access:https://www.mdpi.com/2673-9992/14/1/111