Antitumor and antiangiogenic activity of the novel chimeric inhibitor animacroxam in testicular germ cell cancer

Antitumor and antiangiogenic activity of the novel chimeric inhibitor animacroxam in testicular germ cell cancer

Chimeric inhibitors, which merge two drug pharmacophores in a single molecule have become a prominent approach for the design of novel anticancer compounds. Here, we examined animacroxam, which combines histone deacetylase (HDAC) inhibitory and cytoskeleton‐interfering pharmacophores, in testicular...

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Bibliographic Details
Main Authors: Gustav Steinemann, Alexandra Dittmer, Jacob Schmidt, David Josuttis, Michael Fähling, Bernhard Biersack, Nicola Beindorff, Eva Jolante Koziolek, Rainer Schobert, Winfried Brenner, Thomas Müller, Bianca Nitzsche, Michael Höpfner
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Molecular Oncology
Subjects:
cancer therapy
chick chorioallantoic membrane
HDAC inhibitors
PET/MR imaging
tumor angiogenesis
Online Access:https://doi.org/10.1002/1878-0261.12582

Internet

https://doi.org/10.1002/1878-0261.12582

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