CMV-independent lysis of glioblastoma by ex vivo expanded/activated Vδ1+ γδ T cells.

CMV-independent lysis of glioblastoma by ex vivo expanded/activated Vδ1+ γδ T cells.

Vδ2(neg) γδ T cells, of which Vδ1+ γδ T cells are by far the largest subset, are important effectors against CMV infection. Malignant gliomas often contain CMV genetic material and proteins, and evidence exists that CMV infection may be associated with initiation and/or progression of glioblastoma m...

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Bibliographic Details
Main Authors: Andrea Knight, Hilal Arnouk, William Britt, G Yancey Gillespie, Gretchen A Cloud, Lualhati Harkins, Yun Su, Mark W Lowdell, Lawrence S Lamb
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3737218?pdf=render

Internet

http://europepmc.org/articles/PMC3737218?pdf=render

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