A cross-talk between integrin β4 and epidermal growth factor receptor induces gefitinib chemoresistance to gastric cancer

A cross-talk between integrin β4 and epidermal growth factor receptor induces gefitinib chemoresistance to gastric cancer

Abstract Background Gastric cancer presents a major health burden worldwide. Therefore, many molecular targeting agents have been evaluated for treatment of gastric cancer. Gefitinib has shown anticancer activity against gastric cancer which work through inhibiting epidermal growth factor receptor (...

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Bibliographic Details
Main Authors: Jia Huafeng, Zhang Deqing, Ding Yong, Zhang Yulian, Hu Ailing
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Cancer Cell International
Subjects:
Integrin β4
EGFR
Gastric cancer
Chemoresistance
Gefitinib
Online Access:http://link.springer.com/article/10.1186/s12935-018-0548-5

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http://link.springer.com/article/10.1186/s12935-018-0548-5

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