JWA binding to NCOA4 alleviates degeneration in dopaminergic neurons through suppression of ferritinophagy in Parkinson's disease

JWA binding to NCOA4 alleviates degeneration in dopaminergic neurons through suppression of ferritinophagy in Parkinson's disease

Parkinson's disease (PD) poses a significant challenge in neurodegenerative disorders, characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). The intricate mechanisms orchestrating DA neurodegeneration in PD are not fully understood, nece...

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Bibliographic Details
Main Authors: Xinxin Zhao, Zhengwei Kang, Ruixue Han, Min Wang, Yueping Wang, Xin Sun, Cong Wang, Jianwei Zhou, Lei Cao, Ming Lu
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Redox Biology
Subjects:
JWA
Ferroptosis
Ferritinophagy
JAC4
Neuroprotection
Parkinson's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172400168X

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http://www.sciencedirect.com/science/article/pii/S221323172400168X

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