Clonal structure of rapid-onset MDV-driven CD4+ lymphomas and responding CD8+ T cells.

Lymphoid oncogenesis is a life threatening complication associated with a number of persistent viral infections (e.g. EBV and HTLV-1 in humans). With many of these infections it is difficult to study their natural history and the dynamics of tumor formation. Marek's Disease Virus (MDV) is a pre...

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Bibliographic Details
Main Authors: William N Mwangi, Lorraine P Smith, Susan J Baigent, Richard K Beal, Venugopal Nair, Adrian L Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3088711?pdf=render