Role of immediate-early genes in synaptic plasticity and neuronal ensembles underlying the memory trace

In the brain, neuronal gene expression is dynamically changed in response to neuronal activity. In particular, the expression of immediate-early genes (IEGs) such as egr-1, c-fos, and Arc is rapidly and selectively upregulated in subsets of neurons in specific brain regions associated with learning...

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Bibliographic Details
Main Authors: Keiichiro eMinatohara, Mika eAkiyoshi, Hiroyuki eOkuno
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00078/full