Discovery of serum biomarkers for diagnosis of tuberculosis by NMR metabolomics including cross-validation with a second cohort

Background: Tuberculosis (TB) is a disease with worldwide presence and a major cause of death in several developing countries. Current diagnostic methodologies often lack specificity and sensitivity, whereas a long time is needed to obtain a conclusive result. Methods: In an effort to develop better...

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Main Authors: R. Conde, R. Laires, L.G. Gonçalves, A. Rizvi, C. Barroso, M. Villar, R. Macedo, M.J. Simões, S. Gaddam, P. Lamosa, L. Puchades-Carrasco, A. Pineda-Lucena, A.B. Patel, S.C. Mande, S. Banerjee, M. Matzapetakis, A.V. Coelho
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Biomedical Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S2319417021000949