Cervical cancer-derived exosomal miR-663b promotes angiogenesis by inhibiting vinculin expression in vascular endothelial cells

Abstract Background Angiogenesis provides essential nutrients and oxygen for tumor growth and has become the main mechanism of tumor invasion and metastasis. Exosomes are nanoscale membrane vesicles containing proteins, lipids, mRNA and microRNA (miRNA), which mediate intercellular communication and...

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Bibliographic Details
Main Authors: Xuewu You, Wenxiong Sun, Ying Wang, Xiaoli Liu, Aihong Wang, Lu Liu, Sai Han, Yu Sun, Junhua Zhang, Lingyu Guo, Youzhong Zhang
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Cancer Cell International
Online Access:https://doi.org/10.1186/s12935-021-02379-9