Crohnâs Disease Fibroblasts Overproduce the Novel Protein KIAA1199 to Create Proinflammatory Hyaluronan FragmentsSummary

Background & Aims: Crohnâs Disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Fibrosis, a serious complication of CD, occurs when activated intestinal fibroblasts deposit excessive amounts of extracellular matrix (ECM) in affected areas. A major component of the ECM is...

Full description

Bibliographic Details
Main Authors: Artin Soroosh, Sami Albeiroti, Gail A. West, Belinda Willard, Claudio Fiocchi, Carol A. de la Motte
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X16000047