Identification of dynamic driver sets controlling phenotypical landscapes

Identification of dynamic driver sets controlling phenotypical landscapes

Controlling phenotypical landscapes is of vital interest to modern biology. This task becomes highly demanding because cellular decisions involve complex networks engaging in crosstalk interactions. Previous work on control theory indicates that small sets of compounds can control single phenotypes....

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Bibliographic Details
Main Authors: Silke D. Werle, Nensi Ikonomi, Julian D. Schwab, Johann M. Kraus, Felix M. Weidner, K. Lenhard Rudolph, Astrid S. Pfister, Rainer Schuler, Michael Kühl, Hans A. Kestler
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Boolean network
Dynamic driver
Cellular phenotype control
Network dynamics
Intervention targets
Implicants
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702200109X

Internet

http://www.sciencedirect.com/science/article/pii/S200103702200109X

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