Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole.
The causative agent of Legionnaires' disease, Legionella pneumophila, employs the intracellular multiplication (Icm)/defective organelle trafficking (Dot) type IV secretion system (T4SS) to upregulate phagocytosis and to establish a replicative vacuole in amoebae and macrophages. Legionella-con...
| Format: | Article |
|---|---|
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2006-05-01
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| Series: | PLoS Pathogens |
| Online Access: | http://dx.doi.org/10.1371/journal.ppat.0020046 |