Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole.

Legionella pneumophila exploits PI(4)P to anchor secreted effector proteins to the replicative vacuole.

The causative agent of Legionnaires' disease, Legionella pneumophila, employs the intracellular multiplication (Icm)/defective organelle trafficking (Dot) type IV secretion system (T4SS) to upregulate phagocytosis and to establish a replicative vacuole in amoebae and macrophages. Legionella-con...

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Bibliographic Details
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2006-05-01
Series:	PLoS Pathogens
Online Access:	http://dx.doi.org/10.1371/journal.ppat.0020046

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