E4orf1 improves adipose tissue-specific metabolic risk factors and indicators of cognition function in a mouse model of Alzheimer’s disease

Abstract Objective Obesity, impaired glycemic control, and hepatic steatosis often coexist and are risk factors for developing dementia, and Alzheimer’s disease (AD). We hypothesized that a therapeutic agent that improves glycemic control and steatosis may attenuate obesity-associated progression of...

Full description

Bibliographic Details
Main Authors: Md Shahjalal Hossain Khan, Marleigh Hefner, Arubala Reddy, Nikhil V. Dhurandhar, Vijay Hegde
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Nutrition & Diabetes
Online Access:https://doi.org/10.1038/s41387-023-00242-6