Identification of epithelial and mesenchymal circulating tumor cells in clonal lineage of an aggressive prostate cancer case

Identification of epithelial and mesenchymal circulating tumor cells in clonal lineage of an aggressive prostate cancer case

Abstract Little is known about the complexity and plasticity of circulating tumor cell (CTC) biology in different compartments of the fluid microenvironment during tumor metastasis. Here we integrated phenomics, genomics, and targeted proteomics to characterize CTC phenotypic and genotypic heterogen...

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Bibliographic Details
Main Authors: Shoujie Chai, Carmen Ruiz-Velasco, Amin Naghdloo, Milind Pore, Mohan Singh, Nicholas Matsumoto, Anand Kolatkar, Liya Xu, Stephanie Shishido, Ana Aparicio, Amado J. Zurita, James Hicks, Peter Kuhn
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00289-1

Internet

https://doi.org/10.1038/s41698-022-00289-1

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