Pathogenesis and management of high molecular risk myeloproliferative neoplasms

Classical myeloproliferative neoplasms (MPNs) are clonal stem cell disorders characterised by driver mutations that affect the constitutive activation of JAK-signalling. Additional mutations to an MPN-driver occur in a large number of patients and have been shown be associated with disease presenta...

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Bibliographic Details
Main Authors: Victoria Y. Ling, Florian H. Heidel, Megan J. Bywater
Format: Article
Language:English
Published: Ferrata Storti Foundation 2024-12-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/11857