Epigenetic models developed for plains zebras predict age in domestic horses and endangered equids

Larison et al. report epigenetic aging models in plains zebras (Equus quagga) using the epigenetic clock and epigenetic pacemaker approaches. Their epigenetic clock allows age to be accurately estimated in endangered sister species, and the pacemaker model identifies an association between inbreedin...

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Bibliographic Details
Main Authors: Brenda Larison, Gabriela M. Pinho, Amin Haghani, Joseph A. Zoller, Caesar Z. Li, Carrie J. Finno, Colin Farrell, Christopher B. Kaelin, Gregory S. Barsh, Bernard Wooding, Todd R. Robeck, Dewey Maddox, Matteo Pellegrini, Steve Horvath
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02935-z