Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort

Type 2 diabetes mellitus (T2DM) can be multifactorial where both genetics and environmental factors play a role. We aimed to investigate the use of polygenic risk scores (PRS) in the prediction of pre-transplant T2DM and post-transplant diabetes mellitus (PTDM) among solid organ transplant (SOT) pat...

Full description

Bibliographic Details
Main Authors: Quenia dos Santos, Preston Leung, Christian W. Thorball, Bruno Ledergerber, Jacques Fellay, Cameron R. MacPherson, Mads Hornum, Cynthia Terrones-Campos, Allan Rasmussen, Finn Gustafsson, Michael Perch, Søren S. Sørensen, Christina Ekenberg, Jens D. Lundgren, Bo Feldt‐Rasmussen, Joanne Reekie
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Molecular Biosciences
Subjects:
type 2 diabetes mellitus
transplant
post-transplant diabetes mellitus
solid organ transplant recipient
polygenic risk score
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1282412/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1282412/full

Similar Items