Emergence of primary NNRTI resistance mutations without antiretroviral selective pressure in a HAART-treated child.

The use of antiretrovirals (ARV) during pregnancy has drastically reduced the rate of the human immunodeficiency virus perinatal transmission (MTCT). As a consequence of widespread ARV use, transmission of drug resistant strains from mothers to their babies is increasing. Ultra-sensitive PCR techniq...

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Bibliographic Details
Main Authors: Elizabeth S Machado, Adriana O Afonso, Dwight V Nissley, Philippe Lemey, Silvia M Cunha, Ricardo H Oliveira, Marcelo A Soares
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2652103?pdf=render