A pulse coupled neural network segmentation algorithm for reflectance confocal images of epithelial tissue.

Automatic segmentation of nuclei in reflectance confocal microscopy images is critical for visualization and rapid quantification of nuclear-to-cytoplasmic ratio, a useful indicator of epithelial precancer. Reflectance confocal microscopy can provide three-dimensional imaging of epithelial tissue in...

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Bibliographic Details
Main Authors: Meagan A Harris, Andrew N Van, Bilal H Malik, Joey M Jabbour, Kristen C Maitland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0122368