Progressive multifocal leukoencephalopathy after durvalumab treatment for acute myeloid leukemia: A consequence of an immune reconstitution inflammatory syndrome?

Progressive multifocal leukoencephalopathy after durvalumab treatment for acute myeloid leukemia: A consequence of an immune reconstitution inflammatory syndrome?

Abstract Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease of the central nervous system resulting from the reactivation of the John Cunningham virus (JCV). PML occurs almost exclusively during profound immune suppression but it can also be observed in immunocompromis...

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Bibliographic Details
Main Authors: Emeline Vinatier, Caroline Poli, Aurélien Giltat, Christopher Nunes‐Gomes, Corentin Orvain, Mathilde Hunault‐Berger, Pascale Jeannin, Sylvain Thépot
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:eJHaem
Subjects:
acute leukemia
immunopathology
immunotherapy
infection
Online Access:https://doi.org/10.1002/jha2.485

Internet

https://doi.org/10.1002/jha2.485

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