Triad of Risk for Late Onset Alzheimer’s: Mitochondrial Haplotype, APOE Genotype and Chromosomal Sex

The brain is the most energetically demanding organ of the body, and is thus vulnerable to even modest decline in ATP generation. Multiple neurodegenerative diseases are associated with decline in mitochondrial function e.g. Alzheimer’s, Parkinson’s, multiple sclerosis and multiple neuropathies. Gen...

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Bibliographic Details
Main Authors: Yiwei Wang, Roberta Brinton
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2016.00232/full