Curcumin attenuates cadmium-induced atherosclerosis by regulating trimethylamine-N-oxide synthesis and macrophage polarization through remodeling the gut microbiota

Background: Studies have shown that cadmium (Cd) exposure primarily occurs through diet, and Cd ingestion is a risk factor for atherosclerosis (AS). However, the underlying mechanism remains unclear. As a target organ, the gastrointestinal tract may play a key role in Cd-induced AS. Additionally, as...

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Bibliographic Details
Main Authors: Jiexin Zhang, Caiwen Ou, Minsheng Chen
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Ecotoxicology and Environmental Safety
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322008971