XIAP Regulates Caspase Activity in Degenerating Axons
Our knowledge of the destructive events that regulate axonal degeneration is rudimentary. Here, we examine the role of caspases and their endogenous inhibitor, the X-linked inhibitor of apoptosis protein (XIAP), in axonal degeneration of dorsal root ganglion (DRG) axons. We show that caspase-3, casp...
Main Authors: | Nicolas Unsain, Julia M. Higgins, Kristen N. Parker, Aaron D. Johnstone, Philip A. Barker |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-08-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124713003628 |
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