Genetic Manipulation of CB1 Cannabinoid Receptors Reveals a Role in Maintaining Proper Skeletal Muscle Morphology and Function in Mice

Genetic Manipulation of CB1 Cannabinoid Receptors Reveals a Role in Maintaining Proper Skeletal Muscle Morphology and Function in Mice

The endocannabinoid system (ECS) refers to a widespread signaling system and its alteration is implicated in a growing number of human diseases. Cannabinoid receptors (CBRs) are highly expressed in the central nervous system and many peripheral tissues. Evidence suggests that CB1Rs are expressed in...

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Bibliographic Details
Main Authors: Zoltán Singlár, Nyamkhuu Ganbat, Péter Szentesi, Nomin Osgonsandag, László Szabó, Andrea Telek, János Fodor, Beatrix Dienes, Mónika Gönczi, László Csernoch, Mónika Sztretye
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
endocannabinoid system (ECS)
cannabinoid receptor of type 1 (CBR1)
skeletal muscle force
contractility
excitation-contraction coupling (ECC)
mitochondria
Online Access:https://www.mdpi.com/1422-0067/23/24/15653

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https://www.mdpi.com/1422-0067/23/24/15653

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