Orchestrating NK and T cells via tri-specific nano-antibodies for synergistic antitumor immunity

Abstract The functions of natural killer (NK) and T cells in innate and adaptive immunity, as well as their functions in tumor eradication, are complementary and intertwined. Here we show that utilization of multi-specific antibodies or nano-antibodies capable of simultaneously targeting both NK and...

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Bibliographic Details
Main Authors: Qian-Ni Ye, Long Zhu, Jie Liang, Dong-Kun Zhao, Tai-Yu Tian, Ya-Nan Fan, Si-Yi Ye, Hua Liu, Xiao-Yi Huang, Zhi-Ting Cao, Song Shen, Jun Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-50474-y