Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer

Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer

Abstract Background Cancer mortality is mainly caused by organ failure and thrombotic events. It has been demonstrated that NETosis, a chromatin release mechanism implemented by neutrophils, may contribute to these lethal systemic effects. Our aim was to investigate NETosis biomarkers in endometrial...

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Bibliographic Details
Main Authors: Livia Ronchetti, Irene Terrenato, Margherita Ferretti, Giacomo Corrado, Frauke Goeman, Sara Donzelli, Chiara Mandoj, Roberta Merola, Ashanti Zampa, Mariantonia Carosi, Giovanni Blandino, Laura Conti, Anna Maria Lobascio, Marcello Iacobelli, Enrico Vizza, Giulia Piaggio, Aymone Gurtner
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
NETs
NETosis
Circulating cell-free DNA
Citrullinated Histone H3
Neutrophil Elastase
Tumor induced systemic effects
Online Access:https://doi.org/10.1186/s13046-022-02359-5

Internet

https://doi.org/10.1186/s13046-022-02359-5

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