L‐BAIBA Synergizes with Sub‐Optimal Mechanical Loading to Promote New Bone Formation
ABSTRACT The L‐enantiomer of β‐aminoisobutyric acid (BAIBA) is secreted by contracted muscle in mice, and exercise increases serum levels in humans. In mice, L‐BAIBA reduces bone loss with unloading, but whether it can have a positive effect with loading is unknown. Since synergism can be more easil...
Main Authors: | Matt Prideaux, Alberto Smargiassi, Gang Peng, Marco Brotto, Alexander G Robling, Lynda F Bonewald |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2023-06-01
|
Series: | JBMR Plus |
Subjects: | |
Online Access: | https://doi.org/10.1002/jbm4.10746 |
Similar Items
-
Osteocytes regulate senescence of bone and bone marrow
by: Peng Ding, et al.
Published: (2022-10-01) -
Changes in Vertebral Bone Density and Paraspinal Muscle Morphology Following Spaceflight and 1 Year Readaptation on Earth
by: Jennifer C. Coulombe, et al.
Published: (2023-12-01) -
Increased Osteocyte Lacunae Density in the Hypermineralized Bone Matrix of Children with Osteogenesis Imperfecta Type I
by: Matthias Mähr, et al.
Published: (2021-04-01) -
Histological assessment of cortical bone changes in diabetic rats
by: Masataka Minami, et al.
Published: (2022-12-01) -
Changes in cortical bone channels network and osteocyte organization after the use of zoledronic acid
by: Gustavo Davi Rabelo, et al.
Published: (2015-08-01)