SpliceAPP: an interactive web server to predict splicing errors arising from human mutations

SpliceAPP: an interactive web server to predict splicing errors arising from human mutations

Abstract Background Splicing variants are a major class of pathogenic mutations, with their severity equivalent to nonsense mutations. However, redundant and degenerate splicing signals hinder functional assessments of sequence variations within introns, particularly at branch sites. We have establi...

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Bibliographic Details
Main Authors: Ang-Chu Huang, Jia-Ying Su, Yu-Jen Hung, Hung-Lun Chiang, Yi-Ting Chen, Yen-Tsung Huang, Chen-Hsin Albert Yu, Hsin-Nan Lin, Chien-Ling Lin
Format: Article
Language:English
Published: BMC 2024-06-01
Series:BMC Genomics
Subjects:
RNA splicing
Human mutations
Splicing variant prediction
LASSO regression
Online Access:https://doi.org/10.1186/s12864-024-10512-x

Internet

https://doi.org/10.1186/s12864-024-10512-x

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